Xarelto vs Eliquis are two commonly prescribed anticoagulant medications to prevent and treat blood clots. Understanding the differences between these two drugs can help patients and healthcare providers make informed decisions about which medication is right for them.
Xarelto vs Eliquis
Xarelto and Eliquis are both direct oral anticoagulants (DOACs) that work by reducing the effects of Factor Xa, a protein that plays a key role in the blood clotting process. Both drugs are indicated for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF), as well as the treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE).
Efficacy Difference Between Xarelto and Eliquis
Several clinical trials have compared the efficacy of Xarelto and Eliquis for preventing stroke and systemic embolism in patients with NVAF. One study found that both drugs were equally effective at reducing the risk of stroke and systemic embolism, but Eliquis was associated with a lower risk of major bleeding.
When it comes to the treatment and prevention of DVT and PE, both Xarelto and Eliquis have been shown to be effective. In one study, Xarelto was found to be non-inferior to standard therapy with enoxaparin and a vitamin K antagonist for the treatment of DVT, while Eliquis was found to be non-inferior to enoxaparin followed by warfarin for the treatment of DVT and PE.
Are Xarelto and Eliquis Safe?
Both Xarelto and Eliquis carry a risk of bleeding, which is apotential complication of all anticoagulant medications. In general, the risk of bleeding with Xarelto and Eliquis is low, but it is important for patients to be aware of the signs of bleeding and to seek medical attention if they experience any unusual symptoms.
In terms of adverse effects, Xarelto has been associated with an increased risk of gastrointestinal bleeding, while Eliquis has been associated with an increased risk of dyspepsia (indigestion) and nausea. Patients with certain health conditions or risk factors may be more susceptible to these adverse effects.
Cost Difference Between Xarelto vs Eliquis
In terms of pricing, Xarelto costs $189.99 (10mg x 50 tablets), $289.89 (15mg x 90 tablets), and $289.89 (20mg x 90 tablets). Meanwhile, Eliquis costs $119.99 (2.5mg x 180 tablets), and $119.99 (5mg x 180 tablets).
Considerations for Choosing Between Xarelto and Eliquis
When choosing between Xarelto and Eliquis, healthcare providers will consider several factors, including patient-specific factors such as age, condition of the kidney, and other health conditions. They will also take into account physician preferences and clinical practice guidelines. Patients should be aware of these factors and communicate with their healthcare provider to ensure they are receiving the medication that is most appropriate for their individual needs.
Xarelto and Eliquis are both effective anticoagulant medications that can prevent and treat blood clots. While they share many similarities, there are also important differences between the two drugs, including efficacy, safety, cost, and availability. By understanding these differences, patients and healthcare providers can make informed decisions about which medication is right for them.