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Trulicity vs Ozempic

Trulicity vs Ozempic

Trulicity vs Ozempic. Too much sugar in your blood is a common medical issue known as type 2 diabetes. Exercise and a balanced diet are crucial for managing Type 2 diabetes. More often than not, your doctor may prescribe you some medications to help manage your blood sugar levels effectively.

Trulicity (dulaglutide) and Ozempic (semaglutide) are two injectable drugs for Type 2 diabetes. They both function the same way in managing your condition.

But the question is: how are they different? Is one more effective than the other? Continue reading to learn more about the difference between Trulicity and Ozempic.

What Is Trulicity?

Trulicity is used to treat type 2 diabetes manufactured by Eli Lilly and Company and contains the active ingredient dulaglutide.  Adults usually receive a Trulicity injection once per week.

Trulicity cannot treat diabetic ketoacidosis or type 1 diabetes. However, when used according to instructions, it may reduce the risk of various type 2 diabetes-related health issues, such as heart attack, stroke, kidney failure, nerve damage, eye issues, and gum disease.

What Is Ozempic?

Like Trulicity, Ozempic is also often injected once per week to treat type 2 diabetes. It facilitates weight loss by reducing the speed at which the stomach empties.

Additionally, the FDA has approved it for use in chronic weight management. It is produced by Novo Nordisk and contains semaglutide as the active ingredient. When blood sugar levels are high, Ozempic works by assisting the pancreas in releasing the proper quantity of insulin.

What Is The Difference Between Trulicity and Ozempic?

Adults should take Ozempic and Trulicity in addition to thorough diet and fitness plans. It is not recommended to use Trulicity or Ozempic as a quick treatment for type 2 diabetes or weight loss.

Both drugs can lessen the risk of stroke, heart attack, or death among patients with type 2 diabetes who also have heart and blood vessel conditions.

Trulicity is only permitted for use in individuals with type 2 diabetes. On the other hand, the use of Ozempic is allowed in patients with a body mass index (BMI) of 30 or more. Patients who have a BMI of 27 or higher can also take it with a metabolic health issue, such as type 2 diabetes or high blood pressure.

Trulicity vs Ozempic Side Effects


Trulicity’s most frequent side effects include:

  • Diarrhea
  • Nausea
  • Heartburn
  • Diminished appetite
  • Fatigue


The drug Trulicity may have serious adverse effects. Please seek immediate medical attention if you encounter any of the following:

  • Vomiting
  • Hives
  • Rash
  • Persistent stomachache
  • Itching
  • Breathing or swallowing difficulty
  • Lips, tongue, face, or throat swelling
  • Vision problem
  • Rapid heart rate



Ozempic’s common side effects include the following:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Constipation
  • Burping
  • Heartburn


Although uncommon, serious side effects are still possible. Please seek immediate care if you develop any of the following symptoms:

  • Persistent stomach discomfort with or without vomiting that starts in the upper left or center of the stomach and may move to the back
  • Itching and rashes
  • Eye, face, mouth, tongue, or throat swelling
  • Breathing or swallowing issues
  • Legs, ankles, or feet swelling
  • Vision changes
  • Dizziness or fainting
  • Yellowing of the eyes or skin
  • Fever
  • Rapid heart rate


Trulicity vs Ozempic Cost

The price of Trulicity is $886.46 a month, which you would have to pay out of pocket if you have insurance or if your insurer does not cover the medicine. However, you might have to pay $25 a month for the drug if you have insurance.

In contrast, without insurance, Ozempic can cost more than $1,300 per month. With insurance, you might pay as little as $25 a month.

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