Border Free Supply Logo
Border Free Supply

Medical Expert

medications for depression

Top 5 Medications for Depression: Understanding Your Options

Products related to this post

Sarah sat in her therapist’s office, feeling overwhelmed and defeated. Months of therapy had helped her gain insights and coping strategies, but her depression still lingered like a persistent cloud. Her therapist suggested exploring medication as an additional tool to manage her symptoms. Though hesitant at first, Sarah realized she needed to be open to new possibilities and take control of her mental health.

After discussing her options with her psychiatrist, Sarah was introduced to the world of antidepressant medications. She learned that medications could help restore the balance of chemicals in her brain, alleviating some of the symptoms of her depression. Curiosity piqued, she delved deeper into understanding the top medications prescribed for depression, eager to make an informed decision about her treatment.

Depression is a mental health condition that affects millions of people worldwide. While therapy and lifestyle changes play crucial roles in managing depression, medication can also be an important component of treatment. There are various medications available for depression, and understanding your options can help you make informed decisions about your mental health. In this article, we will explore the top five medications commonly prescribed for depression, their mechanisms of action, potential side effects, and their effectiveness in treating depression.

Selective Serotonin Reuptake Inhibitors (SSRIs):

SSRIs are among the most commonly prescribed medications for depression. They work by increasing the levels of serotonin, a neurotransmitter associated with mood regulation, in the brain. Medications like Prozac (fluoxetine), Zoloft (sertraline), and Lexapro (escitalopram) are SSRIs known for their effectiveness in treating depression. Common side effects may include nausea, headaches, and sexual dysfunction.

Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs):

SNRIs are another class of antidepressants commonly prescribed for depression. They work by increasing the levels of serotonin and norepinephrine, another neurotransmitter involved in mood regulation. Medications such as Effexor (venlafaxine), Cymbalta (duloxetine), and Pristiq (desvenlafaxine) fall into this category. Side effects may include sleep disturbances, dizziness, and dry mouth.

Tricyclic Antidepressants (TCAs):

TCAs were among the first medications used to treat depression. Although they are not as commonly prescribed today due to their side effect profile, they can still be effective for some individuals. TCAs, such as amitriptyline, imipramine, and nortriptyline, work by increasing the levels of serotonin and norepinephrine in the brain. Side effects may include dry mouth, blurred vision, and constipation. Monoamine Oxidase Inhibitors (MAOIs):

MAOIs are an older class of antidepressants used when other medications have not been effective. They work by inhibiting the action of monoamine oxidase enzymes, which break down neurotransmitters like serotonin, norepinephrine, and dopamine. Examples of MAOIs include Nardil (phenelzine) and Parnate (tranylcypromine). MAOIs have several dietary restrictions and can interact with other medications, so close monitoring is essential.


Atypical Antidepressants:

Atypical antidepressants are a diverse group of medications that don’t fit into the other categories. They target various neurotransmitters and have different mechanisms of action. Medications such as Wellbutrin (bupropion), Remeron (mirtazapine), and Trazodone are classified as atypical antidepressants. Side effects can vary, but common ones include drowsiness, weight gain, and dry mouth.


When it comes to treating depression, medication can be a vital tool in conjunction with therapy and lifestyle changes. The five categories of medications discussed – SSRIs, SNRIs, TCAs, MAOIs, and atypical antidepressants – offer different options with varying efficacy and side effect profiles. It’s crucial to work closely with a healthcare provider to find the right medication and dosage that suits your specific needs. Remember, finding the most effective treatment for depression may involve some trial and error, and adjustments may be necessary to optimize your mental health.


Disclaimer: This article is for informational purposes only and should not substitute professional medical advice. Always consult with a healthcare provider for personalized guidance and treatment recommendations

Share this post:

Leave a Reply

Your email address will not be published. Required fields are marked *

Sign up for health care tips and news

Receive offers and updates from our team of experts.

Browse Our Experts Advice
Our experts regularly write about ways to improve your health and wellbeing.

Related Products


Price - $177.65$580.50


Price - $119.00$321.30

Search NOW

Can't find what you need?

Find Medication

Find Help & Advice

Find Medication

Find Help & Advice


Any site that offers you medication without a prescription or based on a remote consultation will likely be gone tomorrow. With Border Free Supply, you are sure to receive generics which are produced by Canada and India’s top rated manufacturers.

It is permitted to buy non controlled substance medication for personal use online. Please read the FDA memo for more information on personal importation of medication.

Generic medication is simply a medication that has been manufactured by a different company, rather than the company who originally held the patent on the product. Generic medications work in the exact same manner as brand name medications and are bio-equivalent to their brand name counterparts. Generic versions of medications cost far less because they invest less money on marketing.

India & Turkey have one of the largest pharmaceutical manufacturing industries in the world! In fact, many of these companies are doing contract manufacturing for the North American market, and therefore their facilities are FDA approved. We source our medications only from the top-rated manufacturers who follow GMP guidelines, and produce their medicine in world-class manufacturing facilities. All of the Indian generic medications we sell are approved by the World Health Organization, Pepfar, and the Indian FDA.

Prescriptions are valid for one year or until the refills authorized have been exhausted.

We can send up to a 90 day supply at one time. Ordering a 90 day supply saves on shipping and allows your to have a larged amount of medicaiton on hand at one time.